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Reference ID: 3879293 Certain side effects such methotrexate as mouth sores may be reduced by folate supplementation with methotrexate .
Trimethoprim/sulfa-methoxazole has been reported rarely to increase bone marrow suppression in patients receiving methotrexate, probably by an additive antifolate Carcinogenesis, Mutagenesis, and Impairment of Fertility No controlled methotrexate human data exist regarding the risk of neoplasia with methotrexate .
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